#wikipedia.org. Patapsco River. The Patapsco River ( pÉ™-TAP-skoh ) mainstem is a 39-mile (63 km) river in central Maryland that flows into the Chesapeake Bay. The river's tidal portion forms the harbor for the city of Baltimore. With its South Branch, the Patapsco forms the northern border of Howard County, Maryland. The name "Patapsco" is derived from the Algonquian pota-psk-ut,
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